Candida related research papers - CNSLab

Candida related research papers

  1. Prevalence and Possible Role of Candida Species in Patients with Psoriasis: A Systematic Review and Meta-Analysis (Pietrzak et al, 2018)                                               Research continues to uncover the impact that Candidiasis can have upon human health. Candida antigens, especially Candida albicans surface proteins have demonstrated superantigen-like effects in stimulating the excessive release of proinflammatory cytokines. These yeast-like fungi play a significant role in triggering psoriasis flares, in fact increased Candida colonization has been confirmed in individuals with psoriasis. This is of great clinical importance due to the potential risk for Candida infections during treatment with particular drugs, which significantly affect the antifungal immune response.
  2. Cancer risk in patients with candidiasis: a nationwide population-based cohort study (Chung et al, 2017)                                                                                                                                                  Our study suggested that CI can significantly increase overall and some individual cancer risks, which is partially compatible with previous findings.
  3. Candida albicans exposures, sex specificity and cognitive
    deficits in schizophrenia and bipolar disorder (Severance et al, 2016)                       
     Sex-specific C. albicans immune responses were evident in psychiatric disorder subsets. Yeast exposure as a risk factor for schizophrenia and its associated cognitive and GI effects require further investigation including the possible contribution of gut–brain mechanisms.
  4. How Chemotherapy Increases the Risk of Systemic Candidiasis in Cancer Patients: Current Paradigm and Future Directions (Teoh and Pavelka, 2016)          Systemic candidiasis is highly prevalent in cancer patients and is associated with high morbidity, mortality and healthcare costs.
  5. Different Brain Regions are Infected with Fungi in Alzheimer's Disease                        (Pisa et al, 2015)                                                                                                                                                             The possibility that Alzheimer’s disease (AD) has a microbial aetiology has been proposed by several researchers. Here, we provide evidence that tissue from the central nervous system (CNS) of AD patients contain fungal cells and hyphae.
  6. Invasive candidiasis in intensive care unit; consensus statement from an Iranian panel of experts, July 2013 (Ahmadi et al, 2013)                                                                               Invasive candidiasis (IC) is associated with high mortality in intensive care unit (ICU) patients.