A deeper dive into the science
SUPPORTING SCIENCE
There has been notable scientific evidence surrounding IgG food sensitivity tests in diagnosing food sensitivities and food intolerances.
Science recognised globally for being independent, accurate, rigorous and valid.
Peer reviewed science is a foundational quality control mechanism in the science that underpins food sensitivity and food intolerance testing. By it’s very nature it’s independent, accurate, rigorous and valid – and helps support all the work we we do within the field of IgG food sensitivity testing.
The following is a list, including authors, with links of key external scientific research on IgG food sensitivity testing.
Science supporting IgG food sensitivity testing
Rees, T., Watson, D., Lipscombe, S., Speight, H., Cousins, P., Hardman, G., & Dowson, A. (2005) A prospective audit of food intolerance among migraine patients in primary care clinical practice Headache Care, 2(1), 11
Zhao, Z., Jin, H., Yin, Y., Hou, Y., Wang, J., Tang, C., & Fu, J. (2021) Association of migraine with its comorbidities and food specific immunoglobulin G antibodies and inflammatory cytokines: cross-sectional clinical research Journal of Pain Research, 2359-2368
Alpay, K., Ertaş, M., Orhan, E. K., Üstay, D. K., Lieners, C., & Baykan, B. (2010) Diet restriction in migraine, based on IgG against foods: a clinical double-blind, randomised, cross-over trial. Cephalalgia, 30(7), 829-837
Hardman, G., & Hart, G. (2007) Dietary advice based on food‐specific IgG results Nutrition & Food Science, 37(1), 16-23
Xie, Y., Zhou, G., Xu, Y., He, B., Wang, Y., Ma, R., … & Xiao, Z. (2019) Effects of diet based on IgG elimination combined with probiotics on migraine plus irritable bowel syndrome Pain Research and Management, 2019
Atkinson W, Sheldon TA, Shaath N, Whorwell PJ Food elimination based on IgG antibodies in irritable bowel syndrome: a randomised controlled trial Gut. 2004;53(10):1459-1464
Coucke, F. (2018) Food intolerance in patients with manifest autoimmunity Observational study. Autoimmunity reviews, 17(11), 1078-1080
Zar S, Benson MJ, Kumar D Food-specific serum IgG4 and IgE titers to common food antigens in irritable bowel syndrome American Journal of Gastroenterology. 2005;100(7):1550-1557
Ligaarden SC, Lydersen S, Farup PG IgG and IgG4 antibodies in subjects with irritable bowel syndrome: a case control study in the general population BMC Gastroenterology. 2012;12:166
van de Veen W, Stanic B, Yaman G, et al IgG4 production is confined to human IL-10–producing regulatory B cells that suppress antigen-specific immune responses Journal of Allergy and Clinical Immunology. 2013;131(4):1204-1212
Aalberse RC, Stapel SO, Schuurman J, Rispens T Immunoglobulin G4: an odd antibody Immunoglobulin G4: an odd antibody
Alunno, A., Bistoni, O., Carubbi, F., Valentini, V., Cafaro, G., Bartoloni, E., … & Gerli, R. (2018) Prevalence and significance of anti-saccharomyces cerevisiae antibodies in primary Sjögren’s syndromeClin Exp Rheumatol, 36(112), S73-S79
Mitchell, N., Hewitt, C. E., Jayakody, S., Islam, M., Adamson, J., Watt, I., & Torgerson, D. J. (2011) Randomised controlled trial of food elimination diet based on IgG antibodies for the prevention of migraine like headaches Nutrition journal, 10(1), 1-9
Hicks, K., & Hart, G. (2008) Role for food‐specific IgG‐based elimination diets Nutrition & Food Science, 38(5), 404-416
Mullin, G. E., Swift, K. M., Lipski, L., Turnbull, L. K., & Rampertab, S. D. (2010) Testing for food reactions: the good, the bad, and the ugly Nutrition in clinical practice, 25(2), 192-198
Hvatum, M., Kanerud, L., Hällgren, R., & Brandtzaeg, P. (200 The gut–joint axis: cross reactive food antibodies in rheumatoid arthritis 55(9), 1240-1247
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